Endocrine Abstracts

Retinol-binding protein 4 (RBP4) is considered as an important mediator of insulin resistance and metabolic syndrome (MS). In adipose tissue (AT)) it is mainly secreted from visceral depots. The residual metabolic risk which remains beyond that caused by visceral AT seems to be hold by upper body subcutaneous AT. This large pathogenic depot might be representative by subcutaneous neck AT.The aim of this study was to examine and to compare RBP4 gene expre...

Parathyroid localization by fine needle aspiration and parathyroid hormone (PTH) washout measurement is not a widely accepted method because of possible alterations in parathyroid histology. However, when performed with technical competence this easily available method has been praised to be an immediate confirmation of enlarged parathyroid glands found on ultrasound. We retrospectively reviewed primary hyperparathyroidism (PHPT) patients with previously performed PTH washout ...

Adipokines are an important contributor to the circulatory milieu of the body. The spectrum of adipokines changes as dysfunctional features of adipose tissue develop and the menopause is a time when an impairment of metabolic balance appears. The aim of this study was to examine several serum adipokines and adiponectin gene expression in subcutaneous and deep neck adipose tissue in women. Samples of serum, subcutaneous and deep neck adipose tissue were taken in 41 (12 premenop...

Although primary hyperparathyroidism (PHPT) can be successfully cured by parathyroidectomy (PTX) and indications for surgery are well defined, a considerable number of patients do not get operated on. By evaluating referrals for PTX in our academic hospital, we might improve our approach to the care of these patients. We retrospectively reviewed patients’ hospital records with newly diagnosed PHPT between 2014 and 2020. Biochemical and clinical parameters along with resul...

Adipose tissue is an endocrine organ that actively contributes to the development of the metabolic dysfunction but it is not homogenous and the nature of its impact considerably depends on its anatomic location. So far both subcutaneous and deep neck adipose tissue depots were individually related to increased metabolic risk but their particular features were not mutually compared. Adiponectin is an adipocytokine that has consistently showed higher mRNA expression in subcutane...